Regulation of osteoprotegerin production by androgens and anti-androgens in human osteoblastic lineage cells
نویسندگان
چکیده
منابع مشابه
Regulation of osteoprotegerin production by androgens and anti-androgens in human osteoblastic lineage cells.
BACKGROUND Estrogens and androgens have anti-resorptive effects on bone, although recent evidence indicates that, even in men, estrogen is the dominant sex steroid regulating bone resorption. The receptor activator of NF-kappaB ligand is essential for osteoclastic bone resorption, and its effects are blocked by the decoy receptor, osteoprotegerin (OPG). While estrogen has been shown to induce o...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2002
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1470269